发明名称 Polysulfide compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient.
摘要 <p>A lipid peroxidation inhibitor contains a polysulfide compound represented by formula (I) as an active ingredient: R&lt;1&gt; - (S)m - R&lt;2&gt; (I&gt; wherein R&lt;1&gt; and R&lt;2&gt; are same or different hydrocarbon chains having 1 to 16 carbon atoms and m is an integer of 3 to 10. Among compounds (I) are found novel which are: R&lt;3&gt; - (S)n - R&lt;4&gt; (II&gt; wherein R&lt;3&gt; and R&lt;4&gt; are same or different lower alkenyl groups and n is an integer of 6 to 10. Pharmaceutical compositions which contain a polysulfide compound represented by formula (I) as an active ingredient, for preventing and curing diseases of thrombosis, arteiosclerosis, liver troubles, pulmonary edema, skin troubles, eye troubles and aging are also disclosed.</p>
申请公布号 EP0464521(A2) 申请公布日期 1992.01.08
申请号 EP19910110268 申请日期 1991.06.21
申请人 WAKUNAGA SEIYAKU KABUSHIKI KAISHA 发明人 AWAZU, SHOJI;HORIE, TOSHIHARU;KODERA, YUKIHIRO;NAGAE, SHINJI;MATSUURA, HIROMICHI;ITAKURA, YOICHI
分类号 A61K31/00;A61K31/10;A61P1/16;A61P7/06;A61P3/08;A61P9/08;A61P9/10;A61P37/08;A61P39/00;A61P39/06;C07C321/18;C09K15/10 主分类号 A61K31/00
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