POLYNUCLEOTIDE HYBRIDIZATION ASSAYS EMPLOYING CATALYZED LUMINESCENCE

摘要

A polynucleotide probe, useful for detection and identification of polynucleotide sequences in samples of nucleic acid, is disclosed. It has the formula: (Yl---Yn) wherein Yl through Yn are the same or different nucleotide moieties which collectively form a polynucleotide sequence substantially complementary to a single stranded region of a target polynucleotide analyte; provided that at least one of nucleotide moieties Yl through Yn comprises a nucleotide having an apoluminescer attached thereto.