发明名称 |
DNA probe which reveals a hypervariable region on human chromosome 17 |
摘要 |
A DNA probe p144-D6 is homologous to at least a portion of a hypervariable DNA region located on chromosome 17(17p13) in the human genome. The DNA region displays a restriction fragment length polymorphism when digested with certain restriction endonucleases. Unrelated invididuals often display unique fragment patterns on Southern blots probed with p144-D6. The probe can be used to produce a genetic "fingerprint" for establishing human identity, determining engraftment of bone marrow transplants, determining parentage, and otherwise mapping genes.
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申请公布号 |
US5077400(A) |
申请公布日期 |
1991.12.31 |
申请号 |
US19880238647 |
申请日期 |
1988.08.30 |
申请人 |
STATE OF OREGON . . . OREGON HEALTH SCIENCES UNIVERSITY |
发明人 |
LITT, MICHAEL;KONDOLEON, SOPHIA K. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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