Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives

摘要

There are disclosed compounds of the formula A(CH2)nO-B wherein A is <IMAGE> n is 1-2; B is <IMAGE> <IMAGE> <IMAGE> <IMAGE> wherein R4 and R5 are each, independently, hydrogen or lower alkyl; R6 is hydrogen, halo or nitro; <IMAGE> <IMAGE> R8 is lower alkyl; m is 0-3; and the pharmacologically acceptable salts thereof, and their use in the treatment of inflammatory conditions, such as rheumatoid arthritis, ulcerative colitis, psoriasis and other immediate hypersensitivity reactions; in the treatment of leukotriene-mediated nasobronchial obstructive air-passageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like; and as gastric cytoprotective agents.