发明名称 METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES
摘要 The invention describes a method of synthesizing a compound of the formula <IMAGE> (I) in which X=O or NR, Z=an electron-attracting group, R=H, CN or NO2, R1 +R2+N-C=X=a 5-membered or 6-membered heterocycle, and R3=H, R4=OH or R3+R4=a bond, said method involving intermediates of the formula <IMAGE> (IX) in which R5=H, Br or N(R1)CXR2. This method of synthesis does not involve the epoxide derivative of the chroman. The novel compounds of formula (IX) form a further subject of the invention.
申请公布号 US5071991(A) 申请公布日期 1991.12.10
申请号 US19890456491 申请日期 1989.12.26
申请人 SANOFI 发明人 GARCIA, GEORGES;METTEFEU, DANIEL;ROUX, RICHARD
分类号 C07D311/68;C07D213/64;C07D311/70;C07D405/04 主分类号 C07D311/68
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