NEW PROTEIN-POLYCATION CONJUGATES

摘要

New protein-polycation conjugates are capable of forming soluble complexes with nucleic acids or nucleic acid analogs. The protein portion of these conjugates is a protein capable of linking with a cellular surface protein expressed by cells of the T-cell lineage, so that the complexes thus obtained are absorbed by cells which express the T-cell surface protein. Complexes useful in pharmaceutical compositions contain a therapeutically or gene therapeutically active nucleic acid.