发明名称 |
IDENTIFICATION OF NOVEL DRUGS AND REAGENTS |
摘要 |
Methods for identifying oligonucleotides capable of hybridizing with nucleic acid of an infectious agent are disclosed. In accordance with preferred embodiments, oligonucleotides capable of antisense interaction with RNA which is significant to a bodily state of an animal or which is contributory to a diseased state is identified. Therapeutic, diagnostic and research methods and compositions employing such oligonucleotides are provided. Prior knowledge of the sequence of nucleic acid in the infectious agent is generally not required. |
申请公布号 |
AU7974791(A) |
申请公布日期 |
1991.11.27 |
申请号 |
AU19910079747 |
申请日期 |
1991.04.15 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CHRISTOPHER K MIRABELLI;TIMOTHY VICKERS;DAVID J ECKER |
分类号 |
A61K31/70;A61P31/12;A61P31/22;C12N15/09;C12N15/113;C12Q1/02;C12Q1/68;C12Q1/70;G01N33/50 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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