发明名称 |
NEW PHARMACOLOGICALLY ACTIVE CATECHOL DERIVATIVES |
摘要 |
Compounds of formula (I), wherein R1 is an electronegative substituent such as nitro, halogeno or cyano group and R2 is a group selected from (Ia) and (Ib), wherein R is hydrogen, or an alkyl, cycloalkyl, aralkyl or aryl group, wherein X1, X2, Y and Z are independently oxygen, sulfur of NR, wherein R may be as defined above and pharmaceutically acceptable esters and salts thereof are useful in the prevention or treatment of tissue damage induced by lipid peroxidation. |
申请公布号 |
WO9117151(A1) |
申请公布日期 |
1991.11.14 |
申请号 |
WO1991FI00124 |
申请日期 |
1991.04.26 |
申请人 |
ORION-YHTYMAE OY |
发明人 |
BAECKSTROEM, REIJO;HONKANEN, ERKKI;LINDEN, INGE-BRITT;NISSINEN, ERKKI;PIPPURI, AINO;POHTO, PENTTI;KORKOLAINEN, TAPIO |
分类号 |
C07D233/72;A61K31/00;A61K31/05;A61K31/335;A61K31/357;A61K31/385;A61K31/39;A61K31/41;A61K31/415;A61K31/4164;A61K31/4166;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61K31/495;A61K31/496;A61K31/505;A61K31/513;A61K31/535;A61K31/5377;A61K31/54;A61P3/00;A61P9/00;A61P9/08;A61P9/10;A61P29/00;A61P35/00;A61P37/06;A61P39/00;A61P39/06;A61P43/00;C07C;C07D;C07D233/78;C07D233/86;C07D233/88;C07D233/96;C07D239/40;C07D239/52;C07D239/54;C07D239/60;C07D239/62;C07D263/38;C07D263/44;C07D263/46;C07D263/48;C07D265/06;C07D277/20;C07D277/32;C07D277/34;C07D277/36;C07D277/40;C07D277/42;C07D279/06;C07D317/32;C07D317/34;C07D327/04;C07D339/06 |
主分类号 |
C07D233/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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