| 发明名称 |
Process for preparing mono-n-alkylated polyazamacrocycles |
| 摘要 |
The invention relates to a novel process to prepare selectively mono-N-alkylated polyazamacrocycles which requires an electrophile with between about one and five equivalents of a suitable macrocycle in a solvent which will not promote a proton transfer.
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| 申请公布号 |
US5064956(A) |
申请公布日期 |
1991.11.12 |
| 申请号 |
US19900549791 |
申请日期 |
1990.07.09 |
| 申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
KRUPER, JR., WILLIAM J. |
| 分类号 |
A61K47/48;A61K49/00;A61K51/04;A61K51/10;C07D257/02;C07D259/00;C07D403/06;C07D487/08;C07F15/00 |
主分类号 |
A61K47/48 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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