| 发明名称 |
Pentacyclic triterpenoid compounds as topoisomerase inhibitors or cell differentiation inducers |
| 摘要 |
Pentacyclic triterpenoid compounds such as alpha boswelic acid and its acetate, beta -boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.
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| 申请公布号 |
US5064823(A) |
申请公布日期 |
1991.11.12 |
| 申请号 |
US19900517176 |
申请日期 |
1990.05.01 |
| 申请人 |
RESEARCH TRIANGLE INSTITUTE |
发明人 |
LEE, YUE-WEI;FANG, QI-CHENG;WANG, ZHEN-GUO;LI, DE-HUA;COOK, C. E. |
| 分类号 |
A61K31/19;A61K31/215;A61K31/70;C07C62/06;C07C69/00;C07H15/256 |
主分类号 |
A61K31/19 |
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