发明名称 |
Novel platinum complexes. |
摘要 |
<p>A platinum (II) complex represented by the general formula: <CHEM> [wherein A's are each ammonia or two A's jointly represent 1,2-diaminocyclohexane, 1-amino-1-aminomethylcyclohexane or 1,4-diamino-2-methylbutane; and B's may be same or different and represent <CHEM> (wherein m is 0, 1 or 2; n is 0 or 1; R1 is a C3-C6 alkyl group substituted with one or two hydroxyl groups) or two B's jointly represent <CHEM> (wherein R2 is a C2-C5 alkyl group substituted with one hydroxyl group)]. These platinum (II) complexes have high potencies for use as an antitumor agent.</p> |
申请公布号 |
EP0454042(A2) |
申请公布日期 |
1991.10.30 |
申请号 |
EP19910106490 |
申请日期 |
1991.04.23 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
KOGAWA, OSAMU;IWATA, KENJI;EKIMOTO, HISAO;ISHII, TADASHI;TAKADA, KIMIHIKO |
分类号 |
C07F15/00 |
主分类号 |
C07F15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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