发明名称 |
Chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents. |
摘要 |
<p>The present invention provides a chiral nucleotide analog having the Formula I <CHEM> which is substantially free of the (S)-isomer and pharmaceutically acceptable salts and solvates thereof, and their pharmaceutical compositions, which is useful in the treatment of viral infections, especially those caused by human immunodeficiency virus (HIV).</p> |
申请公布号 |
EP0452935(A1) |
申请公布日期 |
1991.10.23 |
申请号 |
EP19910106239 |
申请日期 |
1991.04.18 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
YU, KUO-LONG;BRONSON, JOANNE J.;MARTIN, JOHN C. |
分类号 |
A61P31/12;A61K31/675;C07F9/6561 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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