发明名称 METHOD FOR PREPARING CIS-(BETA)-PHENYLGLYCIDIC-(2R,3R) ACID
摘要 PCT No. PCT/FR91/00133 Sec. 371 Date Aug. 21, 1992 Sec. 102(e) Date Aug. 21, 1992 PCT Filed Feb. 20, 1991 PCT Pub. No. WO91/13066 PCT Pub. Date Sep. 5, 1991.A method for preparing beta -phenylglycidic-(2R, 3R) acid optionally in the form of salt or ester by precipitation of the salt of the beta -phenylglycidic-(2R,3R) acid with (+)- alpha -methylbenzylamine-(R) in a solution of a mixture of salts of cis and trans beta -phenylglycidic acids with (+)- alpha -methylbenzylamine(R)- and the use of the resulting product for preparing taxol and its analogs.
申请公布号 WO9113066(A3) 申请公布日期 1991.10.17
申请号 WO1991FR00133 申请日期 1991.02.20
申请人 RHONE-POULENC RORER S.A. 发明人 DUCHESNE, JEAN-PIERRE;MULHAUSER, MICHEL
分类号 C07D301/32;C07B57/00;C07C233/87;C07C271/22;C07D301/00;C07D303/48;C07D305/14;C12P17/02;C12P41/00 主分类号 C07D301/32
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