| 摘要 |
<p>A compound having the formula I: <CHEM> in which X is a group of formula: <CHEM> in which R1 is NHR4 in which R4 is H, acyl, alkoxycarbonyl or acyl, R2 is arylene, heteroarylene, alkenylene, CH2, O or NH, or any conbination of these, R3 is H, NH2 or NH-acyl, in the R- or S- configuration, and m and n are each O or an integer from 1 to 5; Y is a group of formula: <CHEM> in which y is an integer ranging from 1 to 12; Z is NH2 or the radical of any of the common alpha-amino acids, or of the amides of such amino acids; and pharmacologically - compatible salts of the compound of formula I; provided that, when Y is Gly, X is other than Lys. The compounds of formula I are useful as platelet aggregation inhibitor.</p> |
