发明名称 |
Hollow granular medicine and its preparation |
摘要 |
A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
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申请公布号 |
US5057323(A) |
申请公布日期 |
1991.10.15 |
申请号 |
US19890367948 |
申请日期 |
1989.06.19 |
申请人 |
SHOWA YAKUHIN KAKO CO., LTD.;KAWASHIMA, YOSHIAKI |
发明人 |
NIWA, TOSHIYUKI;KAWASHIMA, YOSHIAKI;TAKEUCHI, HIROFUMI;ITO, YOJI |
分类号 |
A61K9/00;A61K9/16 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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