| 发明名称 |
MODIFIED BETA ADRENERGIC RECEPTOR |
| 摘要 |
O9/DJP5 18117 TITLE OF THE INVENTION MODIFIED BETA ADRENERGIC RECEPTOR A Modified Beta Adrenergic Receptor having the amino acid residue in position 113 (aspartic acid) substituted by a serine residue has been synthesized. This modified receptor interacts with novel ligands that do not react with the natural Asp 113 containing receptor. Transgenic animals containing this modified receptor will respond to novel ligands which will not interact with the normal receptor.
|
| 申请公布号 |
CA2039540(A1) |
申请公布日期 |
1991.10.04 |
| 申请号 |
CA19912039540 |
申请日期 |
1991.04.02 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
SIGAL, IRVING S. (DECEASED);DIXON, RICHARD A. F.;PATCHETT, ARTHUR A.;STRADER, CATHERINE D.;SUGG, ELIZABETH E. |
| 分类号 |
A01K67/027;C07C215/46;C07K14/705;C12N15/09;C12N15/12;C12N15/85;C12P21/02;C12R1/91;(IPC1-7):C12N15/12;C12N5/10;A23K1/16;A61K38/17 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
