摘要 |
There are provided compounds of formula (I), wherein R<1> represents H, OH or alkoxy; R<2> represents H; in addition, R<1> and R<2> may together represent a second bond between the carbon atoms to which they are attached; R<3> represents methyl, ethyl, propyl or allyl; R<4> represents H, OH, alkyl, alkoxy, halogen, amino, S-alkyl, NHCHO or NHCO-alkyl; n represents 1 or 2; X represents O, (H, OH), (H, H) or =NH; and Y represents an optionally substituted cyclohexyl or substituted cyclopentyl group; with various provisos. The compounds are useful, inter alia, as immunosuppressive agents. |