发明名称 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 5-OXYGENATED HMG-C0A REDUCTASE INHIBITORS
摘要 18070 The present invention is directed to a compound of structural formula (3): (3) which are intermediates useful for the preparation of 5-oxygenated derivatives of lovastatin and analogs at the 8-acyl side chain and 6-position of the polyhydronaphtyl ring. Said derivatives of lovastatin and analogs thereof are useful for the treatment of hypercholesterolemia.
申请公布号 CA2038259(A1) 申请公布日期 1991.09.16
申请号 CA19912038259 申请日期 1991.03.14
申请人 MERCK & CO., INC. 发明人 ANDERSON, ROBERT K.;DECAMP, ANN E.;KING, ANTHONY O.;MILLS, SANDER G.;VOLANTE, RALPH P.;KAWAGUCH, ALAN T.
分类号 A61K31/35;A61K31/351;A61P3/06;C07D309/30;C07F7/18;(IPC1-7):C07D309/30;C07D405/12;C07D413/12;C07D417/12 主分类号 A61K31/35
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