发明名称 |
PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 5-OXYGENATED HMG-C0A REDUCTASE INHIBITORS |
摘要 |
18070 The present invention is directed to a compound of structural formula (3): (3) which are intermediates useful for the preparation of 5-oxygenated derivatives of lovastatin and analogs at the 8-acyl side chain and 6-position of the polyhydronaphtyl ring. Said derivatives of lovastatin and analogs thereof are useful for the treatment of hypercholesterolemia.
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申请公布号 |
CA2038259(A1) |
申请公布日期 |
1991.09.16 |
申请号 |
CA19912038259 |
申请日期 |
1991.03.14 |
申请人 |
MERCK & CO., INC. |
发明人 |
ANDERSON, ROBERT K.;DECAMP, ANN E.;KING, ANTHONY O.;MILLS, SANDER G.;VOLANTE, RALPH P.;KAWAGUCH, ALAN T. |
分类号 |
A61K31/35;A61K31/351;A61P3/06;C07D309/30;C07F7/18;(IPC1-7):C07D309/30;C07D405/12;C07D413/12;C07D417/12 |
主分类号 |
A61K31/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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