Process for the preparation of monofunctionalized cyclic tetramines

摘要

Process for the preparation of monofunctionalized cyclic tertramines of formula I <IMAGE> (I) in which R denotes a saturated or unsaturated, especially polymerizable, organic radical, characterized in that the corresponding tetraazacycloalkane compound (according to formula II) is prepared, in which three of the four nitrogen atoms are bonded via covalent bonds with a single atom or group of intracyclic atoms A, in that this triprotected compound is reacted with an organic compound RX (of formula III), X denoting a nucleophobic group, and in that the tetraazacycloalkane compound which is tri-protected and monofunctionalized on the unprotected nitrogen (according to formula IV) thus obtained is deprotected.