摘要 |
<p>A method of detecting and/or quantitating either or both of the genes localized to the breakpoint of a consistently recurring chromosomal translocation present in a human neoplasm, the fusion DNA which crosses the breakpoint, or their encoded products, as well as reagents useful in the method. In particular, a method of detecting either or both of the genes localized to the t(1;19) breakpoint on chromosome 19 and chromosome 1 in human acute lymphoblastic leukemias, the fusion DNA which crosses the breakpoint or their encoded products.</p> |