| 发明名称 |
Quinoline and pyridine anchors for HMG-CoA reductase inhibitors. |
| 摘要 |
<p>Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase.</p> |
| 申请公布号 |
EP0444533(A2) |
申请公布日期 |
1991.09.04 |
| 申请号 |
EP19910102545 |
申请日期 |
1991.02.21 |
| 申请人 |
E.R. SQUIBB & SONS, INC. |
发明人 |
ROBL, JEFFREY ADAM |
| 分类号 |
A61K31/4425;A61K31/44;A61K31/4406;A61K31/4412;A61K31/4418;A61P3/06;C07D213/55;C07D213/62;C07D213/89;C07D215/12;C07D215/58;C07D221/08;C07D221/16;C07F9/40;C07F9/576;C07F9/58;C07F9/60;C07F9/6558;C07F9/6561 |
主分类号 |
A61K31/4425 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
