摘要 |
PURPOSE:To prepare 2,2-dimethylthiazolidine-4-carboxylic acid efficiently by the action of a microorganism, by using 2-aminothiazolidine-4-carboxylic acid as a raw material. CONSTITUTION:A microorganism, e.g. Achromobacter delmarvae (FERM-P No. 3483), belonging to the genus Achromobacter, Alcaligenes or Bacillus, etc., and having the ability to hydrolyze 2-aminothiazoline-4-carboxylic acid to produce L-cysteine or L-cystine is reacted with an aqueous solution of the 2-aminothiazoline-4-carboxylic acid in 0.1-30% substrate concentration containing 2-40% acetone at 30-50 deg.C and 6-10pH to collect the produced 2,2-dimethylthiazolidine- 4-caboxylic acid. |