发明名称 COMPOSITION TO IMPROVE SURVIVAL OF BIOLOGICAL MATERIALS
摘要 The present invention relates to aqueous compositions of substances, such as organic molecules, which are useful to protect and preserve viable plant or animal cell membrane and tissue exposed to hypothermal and hyperthermal temperatures or nonphysiological chemical conditions, and to modify the freezing process of liquids in biological plant or animal cells or tissue. More specifically, the present invention relates to the use of antifreeze polypeptide or antifreeze glycopeptide which is derived, for example, from the fluid or serum of Arctic and Antarctic fish. Preferred antifreeze compounds are related to those polypeptides having multiple alanine-alanine-threonine- or alanine-alanine-alanine-segments.
申请公布号 WO9110361(A1) 申请公布日期 1991.07.25
申请号 WO1991US00351 申请日期 1991.01.17
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 RUBINSKY, BORIS;DEVRIES, ARTHUR, L.
分类号 A01N1/02;A01N3/00;A61K8/64;A61K47/48;A61Q19/00;C07K14/46;C12N1/04;C12N5/06 主分类号 A01N1/02
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