发明名称 METHOD OF TREATING MUSCLE TENSION, MUSCLE SPASTICITY, ANXIETY WITH 3-ARYLOXY-AZETIDINECARBOXAMIDES
摘要 METHOD OF TREATING MUSCLE TENSION, MUSCLE SPASTICITY AND ANXIETY WITH 3-ARYL- OXYAZETIDINECARBOXAMIDES A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxyazetidinecarboxamides having the formula: wherein Z is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloalkylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof when they are possible.
申请公布号 PH25525(A) 申请公布日期 1991.07.24
申请号 PH19520000334 申请日期 1986.02.26
申请人 A.H. ROBINS COMPANY 发明人 CHANDLER ROY TAYLOR;ALBERT DUNCAN CALE;DAVID NORSEEN JOHNSON;HAROLD FISHER STAUFFER
分类号 C07D205/04;A61K;A61K31/395;A61K31/397;A61K31/40;A61K31/415;A61K31/44;A61K31/4427;A61K31/445;A61K31/495;A61K31/535;A61P25/08;A61P25/20;C07D;C07D205/00;C07D205/02;C07D211/80;C07D213/00;C07D213/63;C07D213/69;C07D213/81;C07D233/00;C07D401/06;C07D401/12;C07D401/14;C07D403/06;C07D413/06 主分类号 C07D205/04
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