Two-wire television interphone system is arranged to discriminate by a line voltage discriminator incorporated in a master device a line voltage variation due to a calling operation on the side of a branch device, to actuate a voltage controller in the branch device to shift the system from standby state to operation state, and to drive a call signal generator in the branch device for actuation of a call signal receiver in the master device. The system is thus made to have a power supply circuit energized for a power supply to the system only when required for effecting the calling operation, talking between the both devices, and so on.