发明名称 MEDICAMENTS, VICINAL DIHYDROXYALKYLXANTHINES CONTAINED THEREIN, PROCESS FOR THE PREPARATION OF THESE XANTHINE COMPOUNDS AND INTERMEDIATE PRODUCTS SUITABLE FOR THESE
摘要 Compounds of the formula (I) wherein one of the radicals R1, R2 or R3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the .omega.,.omega.1 or .omega.-1,.omega.-2 positions and the two other radicals represent straightchain or branched alkyl groups having up to 12 C atoms in the position of R1 and R3 and up to 4 C atoms in the position of R2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.
申请公布号 CA1286292(C) 申请公布日期 1991.07.16
申请号 CA19820412172 申请日期 1982.09.24
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 FURRER, HARALD;ANAGNOSTOPULOS, HIRISTO;GEBERT, ULRICH;HINZE, HEINZ-JOACHIM
分类号 A61K31/52;A61K31/522;A61P11/08;C07C21/04;C07C29/10;C07C31/42;C07D303/08;C07D317/16;C07D317/20;C07D473/06;C07D473/08;C07D473/10 主分类号 A61K31/52
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