CYANOGUANIDINE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF

摘要

CYANOGUANIDINE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF Or the Disclosure The present invention provides a cyanoguanidine derivative which is a precursor for the synthesis of Ncyano-N'-methyl-N"-(2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl)-guanidine (Cimetidine) or its related compound, which has an action of controlling secretion of acid in the stomach based on the histamine H2 receptor antagonism and is valuable as a drug for treating gastric ulcer. This cyanoguanidine derivative is prepared by reacting other cyanoguanidine derivative with a halogenating agent.