| 摘要 |
<p>A compound of formula (I), wherein A?1 and A2¿ are independently N or CH; B is a covalent bond or C=O; R1 is hydrogen or C¿1?-C6 alkyl; R?2¿ is hydrogen, fluorine, chlorine, bromine, trifluoromethyl, C¿1?-C4 alkyl, C1-C4 alkoxy, or C1-C4 alkylthio; R?3¿ is (a) or (b), wherein R4 is phenyl optionally substituted; X is oxygen or sulphur; Y is hydrogen; or Y forms an indole group with the carbon on the ortho position of the phenyl in R4; or a pharmaceutically acceptable base salt thereof when R is hydrogen; with the proviso that when B is a covalent bond, A?1 and A2¿ are each CH, and use for the inhibition of aldose reductase activity.</p> |
