发明名称 |
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摘要 |
Compounds of the formula <IMAGE> wherein R1 is hydrogen or carboxy; Y is -CH2F, -CHF2, -CF3 or -C IDENTICAL CH; and Z is -(CH2)3-NH2, -CH(CH)3- (CH2)2-NH2 or -CH=CH-CH2- NH2; with the proviso that, when R1 is hydrogen, Z is -CH(CH3)-(CH2)2- NH2 and Y is not -CF3; or a lactam thereof when R1 is carboxy; and their salts, are useful in inhibiting the growth of protozoa. They may be administered to animals, e.g. in their drinking water, and, if desired, together with an antiprotozoal agent. |
申请公布号 |
DE3153623(C2) |
申请公布日期 |
1991.06.27 |
申请号 |
DE19813153623 |
申请日期 |
1981.06.12 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC., CINCINNATI, OHIO, US |
发明人 |
SJOERDSMA, ALBERT;MCCANN, PETER P., CINCINNATI, OHIO, US |
分类号 |
A61K31/13;A23K1/16;A61K31/185;A61K31/195;A61K31/505;A61P33/02 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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地址 |
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