| 发明名称 |
New benzodiazepine analogs. |
| 摘要 |
<p>Benzodiazepine analogs of the formula: <CHEM> are disclosed which are antagonists of gastrin and cholecystokinin (CCK) with enhanced aqueous solubility and have properties useful in the treatment of disorders of gastric secretion, appetite regulation, gastrointestinal motility, pancreatic secretion, and dopaminergic function, as well as in treatment producing potentiation of morphine and other opiate analgesics.</p> |
| 申请公布号 |
EP0434369(A1) |
申请公布日期 |
1991.06.26 |
| 申请号 |
EP19900313854 |
申请日期 |
1990.12.18 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
BOCK, MARK G.;EVANS, BEN E.;FREIDINGER, ROGER M. |
| 分类号 |
A61K31/55;A61K31/551;A61K38/00;A61P1/00;A61P1/04;A61P25/20;A61P43/00;C07D243/14;C07D243/16;C07D243/18;C07D243/20;C07D243/22;C07D243/24;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D471/04;C07K5/078 |
主分类号 |
A61K31/55 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
