| 摘要 |
<p>A process for preparing a racemic mixture containing approximately equimolar amounts of stereoisomers of formulae: (I) or salts thereof, wherein R?1, R2, R3, R4, R5, and R6¿ independently represent hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, aromatic heterocyclic or substituted aromatic heterocyclic or a salicylamide moiety, with the proviso that R1 is not hydrogen, alkyl or substituted alkyl, or salts thereof, wherein R?7, R8 and R9¿ independently represent any of the values for R?1, R2, R3, R4, R5 and R6¿, comprising the steps of (a) contacting an optically active compound of formula (II) disclosed herein, (b) heating the resin containing the compounds of formula (II) to a temperature effective to yield the racemic mixture of formulae (I); and (c) recovering the compounds of formulae (I) from the resin.</p> |
