| 发明名称 |
Hydrogenated rapamycin derivatives |
| 摘要 |
A derivative of rapamycin where one, two, or three of the double bonds at the 1-,3-, or 5-positions of rapamycin have been reduced to the corresponding alkane, or a pharmaceutically acceptable salt thereof, which by virtue of its antifungal activity is useful in treating fungal infections. <IMAGE>
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| 申请公布号 |
US5023262(A) |
申请公布日期 |
1991.06.11 |
| 申请号 |
US19900567858 |
申请日期 |
1990.08.14 |
| 申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
CAUFIELD, CRAIG E.;MUSSER, JOHN H.;RINKER, JAMES M. |
| 分类号 |
A61K31/435;A61K31/395;A61P31/04;A61P31/10;C07D311/00;C07D498/18;C07H19/01 |
主分类号 |
A61K31/435 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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