| 发明名称 |
E. COLI SECRETORY STRAINS |
| 摘要 |
Strains of E. coli are provided which are capable of secreting heterologous recombinant proteins through the outer cell wall and directly into the culture medium. Methods are also provided for making and identifying such strains, and for using them to make heterologous proteins that have high biological activity, without the need for cell disruption. |
| 申请公布号 |
AU4644789(A) |
申请公布日期 |
1991.05.31 |
| 申请号 |
AU19890046447 |
申请日期 |
1989.10.31 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
CHARLES A LUNN;SATWANT K NARULA;RICHARD L REIM |
| 分类号 |
C12N1/21;C07K14/245;C07K14/54;C07K16/24;C12N15/00;C12N15/01;C12N15/09;C12N15/16;C12N15/24;C12N15/62;C12N15/70;C12P21/00;C12P21/02;C12R1/19 |
主分类号 |
C12N1/21 |
| 代理机构 |
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代理人 |
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