| 发明名称 |
1-oxaspiro[4,5] decane-7,8-diaminoarylamides |
| 摘要 |
Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents having very high kappa-opioid affinity and selectivity and potency and useful as analgesics, diuretics, antiinflammatory and psychotherapeutic agents are disclosed. Methods for making the compounds and pharmaceutical compositions containing them are also disclosed.
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| 申请公布号 |
US5019588(A) |
申请公布日期 |
1991.05.28 |
| 申请号 |
US19890419991 |
申请日期 |
1989.10.10 |
| 申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
HORWELL, DAVID C.;REES, DAVID C. |
| 分类号 |
C07D295/04;A61K31/40;A61P7/10;A61P25/00;A61P25/04;A61P43/00;C07D295/12;C07D295/135;C07D307/77;C07D307/79;C07D307/83;C07D307/88;C07D333/50;C07D333/74;C07D405/08 |
主分类号 |
C07D295/04 |
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