发明名称 PROCESS FOR THE PREPARATION OF 1-72-CARBETHOXY-4-BENZALKYL AMIDO PHENOXY -3- AMINO -2- PROPANOLS
摘要 1. Claims for the Contracting States : BE CH DE FR GB IT LI LU NL SE Compounds characterized in that they respond to formula : see diagramm : EP0122827,P20,F2 in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; - R2 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; and - n designates an integer less than 5. 1. Claims for the Contracting State : AT A process for preparing novel compounds responding to formula see diagramm : EP0122827,P21,F2 in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with C1 -C5 , branched or not ; - R2 represents a lower alkyl radical with C1 -C5 , branched or not ; and - n designates an integer less than 5, characterized in that said process comprises the step of reacting a base of formula NH2 -R2 where R2 is as defined hereinabove, on a compound of formula (II) without solvent or in a conventional organic solvent such as alcohols, at a temperature of between 20 degrees C and 150 degrees C, see diagramm : EP0122827,P21,F3 R, R', R1 and n being as defined hereinabove.
申请公布号 KR910002945(B1) 申请公布日期 1991.05.11
申请号 KR19840001323 申请日期 1984.03.13
申请人 LABORATOIRES UPSA S.A. 发明人 BOULEY ETIENNE;LACRAMPE JEAN;TEULON JEAN M.
分类号 A61K31/00;C07D303/22 主分类号 A61K31/00
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