发明名称 |
NON-INFECTIOUS HIV-1 PARTICLES AND USES THEREFOR |
摘要 |
<p>HIV-1 mutant constructs which include a mutation in a nucleotide sequence which is present in wild-type HIV-1, in which it is critical in packaging HIV-1, as well as HIV-1 mutant expression products and HIV mutant viral particles, which are non-infectious. Vaccines which are HIV-1 mutant constructs or HIV-1 mutant expression products, as well as a method if immunizing an individual, comprising administering the vaccine in an appropriate amount.</p> |
申请公布号 |
WO9105860(A1) |
申请公布日期 |
1991.05.02 |
申请号 |
WO1990US05932 |
申请日期 |
1990.10.16 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
YOUNG, RICHARD, A.;BALTIMORE, DAVID;ALDOVINI, ANNA;TRONO, DIDIER;FEINBERG, MARK, B. |
分类号 |
A61K39/00;A61K39/21;A61P31/12;C07K14/005;C07K14/155;C07K14/16;C07K14/195;C12N7/00;C12N15/09;C12P21/02;C12R1/91 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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