Endotoxin adsorbent and method of removing endotoxin.

摘要

An endotoxin adsorbent prepared by crosslinking a porous granular chitosan obtained by dispersing an aqueous acidic solution of chitosan into a hydrophobic dispersant and evaporating water under stirring. A method of removing endotoxin from a solution containing only endotoxin as a absorbed material, wherein the pH value of the solution is adjusted to pH 9 or lower than it, and subsequently, the solution is passed through a column packed with a crosslinked granular chitosan. A method of removing endotoxin from a solution containing a protein and endotoxin as absorbed materials, wherein the pH value of the solution is adjusted to equal to or lower than the isoelectric point of the protein and, subsequently, the solution is passed through a column packed with a crosslinked granular chitosan.