发明名称 |
TUMOR NECROSIS FACTOR FORMULATION |
摘要 |
A pharmaceutical composition is prepared utilizing biologically active, selectively conjugated TNF. The conjugation is of TNF to a water-soluble polymer selected from polyethylene glycol polymers or polyoxyethylated polyols, which polyethylene glycol polymer is unsubstituted or substituted at one end with an alkyl group and which polyol is unsubstituted. |
申请公布号 |
CA1283046(C) |
申请公布日期 |
1991.04.16 |
申请号 |
CA19870533061 |
申请日期 |
1987.03.26 |
申请人 |
CETUS CORPORATION |
发明人 |
KATRE, NANDINI;KNAUF, MICHAEL J.;THOMSON, JAMES W. |
分类号 |
A61K38/00;A61K38/19;A61K47/48;A61P35/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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