发明名称 |
TRANSDERMAL NITROGLYCERIN PATCH WITH PENETRATION ENHANCERS |
摘要 |
A transdermal nitroglycerin patch exhibiting superior nitroglycerin skin penetrating characteristics comprising a percutaneous penetration enhancer is disclosed, wherein the penetration enhancer may be one or more of N-methyl-2-pyrrolidone, oleic acid, oleyl alcohol, linoleic acid, isopropyl linoleate, azone and butanediol. Also disclosed is a transdermal patch design comprising two concentric rings, wherein the concentrations of nitroglycerin and the permeability enhancer are varied. |
申请公布号 |
WO9102553(A3) |
申请公布日期 |
1991.04.04 |
申请号 |
WO1990US04456 |
申请日期 |
1990.08.15 |
申请人 |
SCHERING CORPORATION |
发明人 |
GOVIL, SHARAD, K.;RUDNIC, EDWARD, M.;STERNER, DALE, G. |
分类号 |
A61K9/70;A61K31/21;A61K47/10;A61K47/12;A61K47/14;A61K47/22 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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