NUKLEINSYRASONDER SOM INNEHAOLLER EN FOERBAETTRAD MOLEKYLOMKOPPLARE, SAMT BESTAEMNINGSFOERFARANDEN OCH TESTFOERPACKNINGAR INNEHAOLLANDE DEM.

摘要

A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.