| 摘要 |
NEW MATERIAL:The antibiotic substance SF2197C expressed by formula and having the following physical and chemical properties. Appearance, colorless acicular crystal; melting point, 54 deg.C; specific rotation, [alpha] =-37.2 deg. (C=1, methanol); elemental analysis (%), C 59.6, H 9.3, N 11.3; mass spectrometry, molecular ion peak at m/z=440(M<+>) by FD-MS; molecular formula, C22H40N4O5; solubility, soluble in methanol, chloroform, acetone and ethyl acetate and insoluble in water and n-hexane; color reaction, positive to Lemieux, iodine reagent and FeCl3 reagent and negative to ninhydrin reagent; etc. USE:Antibacterial agent. PREPARATION:A microbial strain belonging to genus Actinomadura such as Actinomadura atramentaria (FERM P-7213) is cultured by submerged culture process at 25-32 deg.C for 2-7 days. |
