发明名称 |
Rotating bio-reactor cell culture apparatus |
摘要 |
A bio-reactor system wherein a tubular housing contains an internal circularly disposed set of blade members and a central tubular filter all mounted for rotation about a common horizontal axis and each having independent rotational support and rotational drive mechanisms. The housing, blade members and filter preferably are driven at a constant slow speed for placing a fluid culture medium with discrete microbeads and cell cultures in a discrete spatial suspension in the housing. Replacement fluid medium is symmetrically input and fluid medium is symmetrically output from the housing where the input and the output are apart of a loop providing a constant or intermittent flow of fluid medium in a closed loop.
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申请公布号 |
US4988623(A) |
申请公布日期 |
1991.01.29 |
申请号 |
US19880213559 |
申请日期 |
1988.06.30 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION |
发明人 |
SCHWARZ, RAY P.;WOLF, DAVID A. |
分类号 |
C12M3/02;C12M1/12;C12M3/04;C12M3/06;C12N5/00;C12N5/02;C12N5/06 |
主分类号 |
C12M3/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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