| 摘要 |
<p> beta -Lactam compounds of the formula <CHEM> in which R1 is a cyclic or secondary acyclic amino group which independently has antibacterial activity; R2 is hydrogen, lower alkoxy, lower alkylthio or formamido; R3 is hydrogen or an organic group bonded through carbon, oxygen, sulfur or nitrogen; R4 is an electronegative acidic group; or R3 and R4 together form a heterocycle; and R5 is hydrogen or lower alkyl, except when R3 and R4 form a heterocycle, in which case R5 is hydrogen only; and readily hydrolyzable esters and pharmaceutically acceptable salts of these compounds, and hydrates of any of the foregoing. The products have antibacterial activity.</p> |
