DRY CREATININE ANALYTICAL ELEMENT AND METHOD FOR ITS USE
摘要
DRY CREATININE ANALYTICAL ELEMENT AND METHOD FOR ITS USE Herein disclosed is a multilayer analytical element comprising a support having thereon in the following order: a) a first reagent layer comprising sarcosine oxidase, a rate limiting amount of creatinine amidohydrolase; a peroxidative substance and imidazole leuco dye which is capable providing a detectable dye in the presence of said peroxidative substances and hydrogen peroxide; b) a second reagent layer containing creatinine amidinohydrolase; and c) a porous spreading layer; characterized in that a high NEG oxidase activity sarcosine oxidase having an activity of at least 300 I.U./m2 relative to N-ethyl glycine is present in i) the porous spreading layer; ii) a separate layer between the spreading layer and the layer containing creatine amidinohydrolase; iii) the layer containing creatine amidinohydrolase or iv) all of such layers i) - iii).
申请公布号
CA2017524(A1)
申请公布日期
1991.01.21
申请号
CA19902017524
申请日期
1990.05.25
申请人
DETWILER, RICHARD L.;DAGGETT, STEPHEN G.;ARTER, THOMAS C.;FRICKER, ROBERT F.;FERRIS, ROBERT J.
发明人
DETWILER, RICHARD L.;DAGGETT, STEPHEN G.;ARTER, THOMAS C.;FRICKER, ROBERT F.;FERRIS, ROBERT J.