发明名称 |
METHOD OF 3-(3-PYRIDYLE)-1H,3H-PYRROLO (1,2-0)-THIAZOLE-7-CARBOXYLIC DEXTROROTARY ACID PRODUCTION |
摘要 |
<p>Process for the preparation of the acid of formula (I) by reaction of an ester of 2-chloroacrylic acid with an organic salt of cis or predominantly cis 3-formyl-2-(3-pyridyl)thiazolidine-4-carboxylic acid in the presence of an acid chloride and of triethylamine, and the ester of formula (VII) obtained is then saponified. …<IMAGE>… </p> |
申请公布号 |
CS272240(B2) |
申请公布日期 |
1991.01.15 |
申请号 |
CS19880004762 |
申请日期 |
1988.07.01 |
申请人 |
RHONE-POULENC SANTE,FR |
发明人 |
RAJOHARISON HARIVELO G.,FR |
分类号 |
A61K31/428;A61K31/4406;A61K31/4427;A61P7/02;A61P29/00;A61P37/08;C07D513/04;(IPC1-7):C07D513/04 |
主分类号 |
A61K31/428 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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