发明名称 Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
摘要 New derivatives of chenodeoxycholic, ursodeoxy cholic, cholic and ursocholic acids, bearing a methyl group in the side chain in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described. The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.
申请公布号 US4981983(A) 申请公布日期 1991.01.01
申请号 US19890415614 申请日期 1989.10.02
申请人 GIPHARMEX S.P.A. 发明人 CASTAGNOLA, VIRGINIO;FRIGERIO, E. GIULIANO;PELLICCIARI, ROBERTO;RODA, ALDO
分类号 C07J9/00;C07J51/00 主分类号 C07J9/00
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