发明名称 Buffered metronidazole compositions for intravaginal treatment of vaginal infections.
摘要 <p>A composition and method for treatment of bacterial vaginosis and/or trichomoniasis are disclosed. An afflicted vagina is treated with a therapeutically effective amount of a buffered metronidazole composition having a pH in the range of about 3 to about 4.25, preferably about 3.75 to about 4.25. A preferred such composition comprises metronidazole, a gelled hydrophobic and water-dispersible polymer, such as a polyacrylic acid polymer having a molecular weight in the range of about 1,250,000 to about 4,000,000 daltons, and an aqueous solvent for the metronidazole.</p>
申请公布号 EP0404376(A2) 申请公布日期 1990.12.27
申请号 EP19900306026 申请日期 1990.06.05
申请人 CURATEK PHARMACEUTICALS 发明人 BORGMAN ROBERT J
分类号 A61K31/4164;A61K;A61K9/00;A61K9/02;A61K9/08;A61K9/107;A61K9/12;A61K9/20;A61K31/41;A61K31/415;A61K47/12;A61K47/32;A61P13/02;A61P15/00;A61P29/00;A61P31/04;A61P33/02;A61P33/04 主分类号 A61K31/4164
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