| 摘要 |
The present invention relates to the preparation of new 1-(aminophenyl)-2-aminopropanone derivatives of the general formula: <IMAGE> (I) in which X is NH2, Y is H or a halogen atom, Z is H or a halogen atom, R1 is C1-C4 alkyl or C3-C6 cycloalkyl and R2 is H or C1-C4 alkyl, or R1 and R2, taken together, can form, with the nitrogen atom to which they are bonded, a heterocyclic group selected from the group consisting of the pyrrolidino, morpholino, thiomorpholino, piperidino, hexamethyleneimino, piperazino, 4-methyl-piperazino, 4-( beta -hydroxyethyl)piperzaino, 4-phenylpiperazino and 4-(p-chlorophenyl)piperazino groups, and addition salts thereof. These new derivatives are useful as pharmaceuticals. They are obtained by deacetylation of the corresponding acetylated products.
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