发明名称 SUBSTITUTED BENZYL ETHERS,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 1. Substituted benzyl ethers of the formula see diagramm : EP0224086,P51,F1 in which R**1 and R**2 are identical or different and represent hydrogen, C1 to C8 -alkyl, C2 to C6 -alkenyl, cyclopentyl, cyclohexyl, C1 to C6 -alkoxy, C1 to C6 -alkylthio, halogeno-C1 to C6 -alkyl, halogeno-C1 to C6 -alkoxy, halogeno-C1 to C6 -alkylthio, benzyloxy, benzylthio, fluorine, chlorine, bromine, nitro, cyano or hydroxyl, or represent a group of the formula see diagramm : EP0224086,P51,F2 wherein R**4 and R**5 are identical or different and represent hydrogen, C1 to C8 -alkyl, C2 to C6 -alkenyl, cyclopentyl, cyclohexyl, benzyl, phenyl, benzoyl or acetyl, R**3 represents a group of the formula see diagramm : EP0224086,P51,F3 see diagramm : EP0224086,P51,F4 or see diagramm : EP0224086,P51,F5 wherein R**5 represents hydrogen, benzoyl or C1 to C6 -alkyl-CO-, R**7 , R**7' and R**7" are identical or different and represent hydrogen or C1 to C8 -alkyl, and n represents a number from 3 to 8, B represents -CH2 -X-, wherein X represents O, S or NR**7 , and wherein R**7 has the abovementioned meaning, and the group of the formula see diagramm : EP0224086,P51,F6 represents quinoline, isoquinoline, cinnoline, quinoline N-oxide, quinoxaline, phthalazine, quinolone, isoquinolone, cinnolinone, quinazolinedione, quinoxazolinone, quinoxalinedione, phthalazinedione, indole, indolone, isoindole, isoindolone, benzofuran, benzothiophene, benzimidazole, benzoxazole, benzothiazole, indazole or indoxyl.
申请公布号 IL80624(A) 申请公布日期 1990.12.23
申请号 IL19860080624 申请日期 1986.11.13
申请人 BAYER AKTIENGESELLSCHAFT 发明人
分类号 A61K31/425;A61K31/47;C07D215/18;C07D215/22;C07D215/24;C07D215/26;C07D215/28;C07D215/36;C07D215/38;C07D215/40;C07D215/60;C07D217/02;C07D277/64;C07D277/76 主分类号 A61K31/425
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