2-Benzyl-4-(4-pyridyl)thiazoles and derivatives thereof have been made from converting a benzyl cyanide to the corresponding thioamide followed by condensation with a 4-bromoacetylpyridine. The thiazole derivatives are found to be effective immunoregulants.
申请公布号
DE3580317(D1)
申请公布日期
1990.12.13
申请号
DE19853580317
申请日期
1985.07.18
申请人
MERCK & CO., INC., RAHWAY, N.J., US
发明人
BOULTON, DAVID A., EDISON NEW JERSEY 08817, US;MOORE, VERNON L., SCOTCH PLAINS NEW JERSEY 07076, US;KOPKA, IHOR E., NEWARK NEW JERSEY 07106, US;PESSOLANO, ARSENIO A., COLONIA NEW JERSEY 07067, US